Alper Lab News

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Check out our latest article on the rapid dynamics of the TPP riboswitch - Ensemble switching unveils a kinetic rheostat mechanism of the eukaryotic thiamine pyrophosphate riboswitch !

April 16, 2021

Check out our latest preprint on the rapid dynamics of the TPP riboswitch - Ensemble Switching Unveils a Kinetic Rheostat Mechanism of the Eukaryotic Thiamine Pyrophosphate Riboswitch !

March 12, 2021

Thank you to Apurba on his last day in the lab. He will be joining the Timp Lab at Notre Dame. We wish him the best on his future endeavors!

November 13, 2020

The Alper Lab has been awarded a pilot project in the SC-BIOCRAFT COBRE to pursue work on tissue engineered substrates constructed from cytoskeletal elements and modeled as active matter.

September 13, 2020

Welcome to Lucy Fischer. She is an undergraduate in Biochemistry and will be working on our axonemal dyneine project!

August 19, 2020

Welcome to George Grow. He is an undergraduate in bioengineering and will be working on our optical tweezers and microelectrode array to study the ability of the optical tweezer laser to guide the growth of neuronal processes!

August 19, 2020

Welcome to Jerry Enverso. He is an undergraduate in microbiology and will be working on culturing trypanosome cells at high density!

August 17, 2020

Welcome to Nathan Edwards. He is an undergraduate in Bioengineering and will be working on our neuronal circuitry project!

July 25, 2020

Welcome to Maureen Buckley. She is an undergraduate in bioengineering and will be working on developing an optical tweezer computational model to investigate axonemal dynein-based active matter!

May 19, 2020

We would like to congratulate Katherine, Valerie, Andrew, and Samantha M on graduating this May.

May 8, 2020

Welcome to Yugantar Gera. He is an undergraduate in physics and will be working on our neuronal circuitry project!

May 6, 2020

We would like to congratulate Dr. Alper for winning the 2020 Clemson College of Science Excellence in Teaching award.

May 2, 2020

Welcome to Shira Karni. She is an undergraduate in biochemistry and will be working on our neuronal circuitry project!

January 3, 2020

Archived News...

Welcome to the Alper Lab

Our goal is to understand fundamental physical principles that bridge the atomic, molecular, and cellular scales. We focus on three systems: 1. the eukaryotic cytoskeleton, in particular cilia and flagella, 2. unique biophysical mechanisms of pathogenic parasites, and 3. simple neuronal circuits.


(top left) Chlamydomonas cell with two cilia, (top right) three trypanosome cells with flagella bound to their cell bodies, (bottom) SH-SY5Y neuronal cells.


We are an interdisciplinary research group. We use techniques and models from physics, biophysics, optics, bioengineering, cell biology, molecular biology, biochemistry, and genetics. We are always on the lookout for postdocs, graduate students, and undergraduates with these backgrounds and interests. If you are interested in joining, contact us!

Alper Lab Future Events

The Alper lab will host an REU student this summer as part of the Clemson Biophysis REU.

May 24, 2021

Alper Lab Past Events

Katherine and Subash presented their work at the 30th Annual Molecular Parasitology & Vector Biology Symposium virtually at the University of Georgia's Center of Tropical and Emerging Global Diseases.

May 4, 2021

Subash and Megan presented their work virtually at the 65th Annual Meeting of the Biophysical Society.

February 22-26, 2021

Members of the Alper Lab attended and Ashok presented his work at Cell Bio Virtual 2020.

December 2-16, 2020

Katherine virtually attended and presented her work at the Triangle Cytoskeleton Meeting.

November 2, 2020

Members of the Alper Lab attended and Apurba presented at the virtual Cellular Biology of Eukaryotic Pathogens Meeting in Clemson, SC.

October 30, 2020

Members of Alper Lab attended the PLM 15 meetings virtually.

October 1-2, 2020

Dr. Alper gave a talk at SWU in Natural Sciences Seminar Series.

September 18, 2020

Members of Alper Lab will attended the EMBO 2020 Symposia for microtubules.

June 3-6, 2020

Older Events...